Back to search

Article

Histopathology-assisted proteogenomics provides foundations for stratification of melanoma metastases

2023-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Here we describe the histopathology-driven proteogenomic landscape of 142 treatment-naïve metastatic melanoma samples. We identified five proteomic subtypes that integrate the immune and stroma microenvironment components, and associate with clinical and histopathological parameters, providing foundations for an in-depth molecular classification of melanoma. Our study shows that BRAF V600 mutate...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
dbf711ea-59ec-5a60-bf1c-39da335e2f03
DOI
10.1101/2023.09.29.559755
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Histopathology-assisted proteogenomics provides foundations for stratification of melanoma metastasesDOI 10.1101/2023.09.29.559755
Select a neighboring publication to make it the new centre.