Article

Integrative Multi-Omics Analysis of Melanoma: Uncovering Pathways Associated with Immunotherapy Outcomes

2025-04-07

Abstract excerpt

<h4>Purpose</h4> The treatment of advanced malignant melanoma with immune checkpoint blockade (ICB) therapies such as anti-CTLA4 and anti-PD1 has been transformative, yet a significant proportion of patients demonstrate intrinsic resistance or develop severe immune-related adverse events (irAEs), complicating treatment strategies. This study aimed to integrate clinical and molecular data using multi-omics factor...

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Literature Corpus work: 12a55a9e-41e0-5abe-8117-7d712bf062d2
DOI: 10.1101/2025.04.01.646686

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