Article

Non-permissive CHO cells; A rapid approach for purification of recombinant Herpes Simplex Virus-1

2023-07-07

Abstract excerpt

<title>Abstract</title> <p>Exploiting herpes simplex virus type 1 (HSV-1) has recently emerged as a new strategy to improve the treatment of patients with various cancers resistant to chemotherapy and associated with a poor prognosis due to its ability to infect tumor cells without causing harm to healthy cells. It has been suggested as a new platform for cancer therapy. Gene-modification techniques such as conve...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dbe24285-4337-5bec-b5c4-4a3d4d1d5f74
DOI: 10.21203/rs.3.rs-2966832/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Non-permissive CHO cells; A rapid approach for purification of recombinant Herpes Simplex Virus-1DOI 10.21203/rs.3.rs-2966832/v1Read

Engineered CHO cells as a novel AAV production platform for gene therapy deliverySemantic proximity Read

Transgene Expression in Cultured Cells Using Unpurified Recombinant Adeno-Associated Viral VectorsSemantic proximity Read

Cell Cultures for Virology: Usability, Advantages, and ProspectsSemantic proximity Read

CLEAR Strategy Inhibited HSV Proliferation Using Viral Vectors Delivered CRISPR-Cas9Semantic proximity Read

Time- and Cost-effective Production of Untagged Recombinant Mva by Flow Virometry and Direct Virus SortingSemantic proximity Read

Suppression of HSV-1 infection and viral reactivation by CRISPR-Cas9 gene editing in 2D and 3D culture modelsSemantic proximity Read

Bacterial-Artificial-Chromosome-Based Genome Editing Methods and the Applications in Herpesvirus ResearchSemantic proximity Read

Optimization of the intron sequences combined with the CMV promoter increases recombinant protein expression in CHO cellsSemantic proximity Read

Recombinant adeno‐associated virus production evaluation in Chinese hamster ovary cellsSemantic proximity Read

Generation and characterization of Japanese encephalitis virus expressing GFP reporter gene for high throughput drug screeningSemantic proximity Read

Scalable Recombinant Adeno-Associated Virus Production Using Recombinant Herpes Simplex Virus Type 1 Coinfection of Suspension-Adapted Mammalian CellsSemantic proximity Read

Development of a rapid and quantitative method for the analysis of viral entry and release using a NanoLuc luciferase complementation assaySemantic proximity Read