Article

Sex- and Depression-specific Effects of Non-pathogenic CAG Repeats in <i>HTT</i> , <i>ATXN3</i> and <i>CACNA1A</i> on Sleep

2025-11-27

Abstract excerpt

The effects of non-pathogenic cytosine-adenine-guanine (CAG) repeat sizes on sleep remain unclear, although disrupted sleep has been observed in patients with pathogenic CAG expansions in polyglutamine disease-associated genes (PDAGs), particularly in HTT , ATXN3, and CACNA1A . Here, we assessed the associations between CAG repeat sizes of the three genes and self-reported sleep outcomes in the Netherlands Epid...

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Literature Corpus work: dbde6be4-8cea-58a5-8742-8b79876ad0c7
DOI: 10.1101/2025.11.26.25341069

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