Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations of a multidimensional polygenic sleep health score and a sleep lifestyle index with disease outcomes and their interaction in a clinical biobank.

Sleep health - 1 Jun 2025

Paz Valentina, Wilcox Hannah, Goodman Matthew, Wang Heming, Garfield Victoria, Saxena Richa, Dashti Hassan S

Abstract excerpt

OBJECTIVES: Sleep is a complex behavior regulated by genetic and environmental factors impacting disease outcomes. However, the effect of multidimensional sleep encompassing several sleep dimensions on common diseases, specifically mental health disorders, has yet to be fully elucidated. Using the Mass General Brigham Biobank, we examined the association of multidimensional sleep with disease outcomes and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biological Specimen Banks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Life Style

Share to Mental Disorders

Share to Multifactorial Inheritance

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 40222844
DOI: 10.1016/j.sleh.2025.02.009
PMCID: PMC13229604

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations of a multidimensional polygenic sleep health score and a sleep lifestyle index with disease outcomes and their interaction in a clinical biobank.PMID 40222844Read ↗

Associations of a multidimensional polygenic sleep health score and a sleep lifestyle index on health outcomes and their interaction in a clinical biobankSemantic proximity Read ↗

The associations between sleep behaviors, lifestyle factors, genetic risk and mental disorders: A cohort study of 402 290 UK Biobank participants.Semantic proximity Read ↗

Polygenic risk score identifies associations between sleep duration and diseases determined from an electronic medical record biobankSemantic proximity Read ↗

Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits.Semantic proximity Read ↗

Healthy Lifestyle including Sleep Patterns, Genetic Risk, and Risk of Cardiometabolic MultimorbiditySemantic proximity Read ↗

Genome-wide association analysis of composite sleep health scores in 413,904 individualsSemantic proximity Read ↗

Multivariate genome-wide association study of sleep health demonstrates unity and diversity.Semantic proximity Read ↗

Modeling Sleep Genetics Uncovers Distinct Disease Risks in Night vs. Day WorkersSemantic proximity Read ↗

Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancementSemantic proximity Read ↗

Allostatic load, sleep patterns, and genetic susceptibility in relation to severe mental illness: A prospective cohort study.Semantic proximity Read ↗

Phenome-wide associations of sleep characteristics in the Human Phenotype Project.Semantic proximity Read ↗

From Normal Variation in Sleep to Clinical Sleep Disorders: Genetic Insights from Over One Million IndividualsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.