Article

Integrative omics analysis identifies subtypes with therapeutic implications in lung adenocarcinoma harboring KEAP1/NFE2L2

2021-03-03

Abstract excerpt

<h4>Backgrounds: </h4> Lung adenocarcinoma is one of the most common malignant tumors, in which KEAP1 - NFE2L2 pathway is altered frequently. The biological features and intrinsic heterogeneities of KEAP1 / NFE2L2 -mutant lung adenocarcinoma remain unclear. <h4>Methods: </h4> Multiplatform data from The Cancer Genome Atlas (TCGA) were adopted to identify two subtypes of lung adenocarcinoma harboring KEAP1 / NFE2L2...

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Literature Corpus work: dbbbd334-c33c-5a50-9fd6-39a1600810bc
DOI: 10.21203/rs.3.rs-182066/v1

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