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Article

Integrated analysis of patients with KEAP1/NFE2L2/CUL3 mutations in lung adenocarcinomas.

Cancer medicine - 1 Dec 2021

Jin Xing, Zheng Yuansheng, Chen Zhencong, Wang Fei, Bi Guoshu, Li Ming, Liang Jiaqi, Sui Qihai, Bian Yunyi, Hu Zhengyang, Qiao Yulei, Xu Songtao

Abstract excerpt

OBJECTIVES: To explore the clinical features, molecular characteristics, and immune landscape of lung adenocarcinoma patients with KEAP1/NFE2L2/CUL3 mutations. METHODS: The multi-omics data from the GDC-TCGA LUAD project of The Cancer Genome Atlas (TCGA) database were downloaded from the Xena browser. The estimate of the immune infiltration was implemented by using the GSVA analysis and CIBERSORT. The status of...

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Identifiers

PMID: 34617407
DOI: 10.1002/cam4.4338
PMCID: PMC8633244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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