Article

Detection of human adaptation during the past 2,000 years

2016-05-07

Abstract excerpt

Detection of recent natural selection is a challenging problem in population genetics, as standard methods generally integrate over long timescales. Here we introduce the Singleton Density Score (SDS), a powerful measure to infer very recent changes in allele frequencies from contemporary genome sequences. When applied to data from the UK10K Project, SDS reflects allele frequency changes in the ancestors of modern...

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Literature Corpus work: dba99401-3568-5a64-88c8-20ec1fa68871
DOI: 10.1101/052084

Open publication

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