Article

Gut-resident C. perfringens impedes rotavirus vaccine efficacy

2024-06-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background & Aims</h4> The extent to which live orally-administered rotavirus (RV) vaccines elicit protective immunity is highly heterogeneous. We hypothesized microbiota composition might influence vaccine efficacy. <h4>Methods</h4> We tested this concept by examining extent to which colonizing mice with segmented filamentous bacteria (SFB) influenced RV vaccine efficacy.Influence of huma...

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Literature Corpus work: db94f8bd-ff98-53ce-900b-19bb9bf483cb
DOI: 10.1101/2024.06.17.599343

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