Article
The Role of Host Glycobiology and Gut Microbiota in Rotavirus and Norovirus Infection, an Update.
International journal of molecular sciences - 15 Dec 2021
Peña-Gil Nazaret, Santiso-Bellón Cristina, Gozalbo-Rovira Roberto, Buesa Javier, Monedero Vicente, Rodríguez-Díaz Jesús
Abstract excerpt
Rotavirus (RV) and norovirus (NoV) are the leading causes of acute gastroenteritis (AGE) worldwide. Several studies have demonstrated that histo-blood group antigens (HBGAs) have a role in NoV and RV infections since their presence on the gut epithelial surfaces is essential for the susceptibility to many NoV and RV genotypes. Polymorphisms in genes that code for enzymes required for HBGAs synthesis lead to...
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