Article

Sub-clinical exposure to <i>Streptococcus pyogenes</i> drives the development of immunity

2025-07-02

Abstract excerpt

<h4>Summary</h4> Age-related decline in Streptococcus pyogenes infection rates suggests that immunity develops progressively through repeated exposure during early life. However, the intensity or duration of exposure required is unknown, as to why some individuals appear to develop immunity, despite having few or no previously detected infections. Here, drawing on samples from a human challenge model of pharynge...

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Literature Corpus work: db26672a-c30e-5159-b792-99bc9849b4f2
DOI: 10.1101/2025.07.02.662868

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