Article

Computational Decomposition of New Memory Failure in Alzheimers Disease Through a Hippocampal Cortical Consolidation Bottleneck Model

2026-06-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Alzheimers disease (AD) is characterised by difficulty retaining newly learned information, but routine memory scores often conflate poor initial encoding with impaired post-encoding stabilisation. This study aimed to develop an interpretable computational phenotype that separates new-memory failure during progression from mild cognitive impairment (MCI) to AD. <h4>Methods</h...

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Literature Corpus work: db0abbcc-c874-54b9-8dca-6deea67b25b1
DOI: 10.64898/2026.06.23.26356309

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