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Article

Computational Phenotyping of Cognitive Decline With Retest Learning.

The journals of gerontology. Series B, Psychological sciences and social sciences - 10 Jun 2025

Oravecz Zita, Vandekerckhove Joachim, Hakun Jonathan G, Kim Sharon H, Katz Mindy J, Wang Cuiling, Lipton Richard B, Derby Carol A, Roque Nelson A, Sliwinski Martin J

Abstract excerpt

OBJECTIVES: Cognitive change is a complex phenomenon encompassing both retest-related performance gains and potential cognitive decline. Disentangling these dynamics is necessary for effective tracking of subtle cognitive change and risk factors for Alzheimer's Disease and Related Dementias (ADRD). METHOD: We applied a computational cognitive model of learning and forgetting to data from Einstein Aging Study...

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Identifiers

PMID: 39964977
DOI: 10.1093/geronb/gbaf030
PMCID: PMC12214872

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