Modulation of Transferrin receptor by HIV-2

Abstract excerpt

Human immunodeficiency viruses (HIV-1 and HIV-2), are the causative agents of the acquired immunodeficiency syndrome (AIDS), that share substantial genomic and structural similarities, yet differ in replication dynamics and disease progression. While HIV-1 primarily enters host cells via CD4 and the chemokine co-receptors CCR5 and CXCR4, HIV-2 engages a broader range of chemokine receptors. The transferrin recepto...

Topics

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• Endocytosis
• HIV Research and Treatment
• Iron Metabolism and Disorders
• Receptors, Transferrin
• Research on Leishmaniasis Studies
• RNA Interference and Gene Delivery
• Transferrin
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

dac910df-0d07-5b59-8a7c-d1b80cee8595

DOI

10.1101/2025.07.03.663036