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Role of Cellular Iron and Oxygen in the Regulation of HIV-1 Infection

1 Mar 2013

Abstract excerpt

Despite efficient antiretroviral therapy, eradication of HIV-1 infection is challenging and requires novel biological insights and therapeutic strategies. Among other physiological and environmental factors, intracellular iron greatly affects HIV-1 replication. Higher iron stores were shown to be associated with faster progression of HIV-1 infection and to inversely correlate with the survival of HIV-1 infected...

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Identifiers

PMID: 23678366
DOI: 10.2217/fvl.13.6

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