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Article

Promises and limits of biopsy-based transcriptomics in kidney transplantation: a clinical utility perspective.

Current opinion in nephrology and hypertension - 1 May 2026

Wellekens Karolien, Debyser Tim, Roufosse Candice, Naesens Maarten

Abstract excerpt

PURPOSE OF REVIEW: Biopsy-based transcriptomics have been proposed as a complement to histopathology in the evaluation of kidney allograft rejection by providing standardized, mechanism-oriented insight into intra-graft immune activity. However, diagnostic performance, interpretability, and clinical relevance vary substantially across rejection phenotypes and clinical contexts. This review critically examines the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41782558
DOI: 10.1097/MNH.0000000000001168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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