Article

Transcriptomic analyses reveal neuronal specificity of Leigh syndrome associated genes

2022-08-05

Abstract excerpt

Leigh syndrome (subacute necrotising encephalomyelopathy) is a rare inherited, complex, and typically early onset mitochondrial disorder with clinical and genetic heterogeneity. It owes its heterogeneous nature to the complex nature of mitochondrial genetics and the significant interactions that occur between the mitochondrial and nuclear genomes. Stepwise developmental regression is a classical feature of patient...

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Literature Corpus work: da955058-f5f2-5d9e-8ce2-f0cd33da14da
DOI: 10.1101/2022.08.05.502943

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