Article
Analysis of 182 cerebral palsy transcriptomes points to dysregulation of trophic signalling pathways and overlap with autism.
Translational psychiatry - 23 Apr 2018
van Eyk Clare L, Corbett Mark A, Gardner Alison, van Bon Bregje W, Broadbent Jessica L, Harper Kelly, MacLennan Alastair H, Gecz Jozef
Abstract excerpt
Cerebral palsy (CP) is the most common motor disability of childhood. It is characterised by permanent, non-progressive but not unchanging problems with movement, posture and motor function, with a highly heterogeneous clinical spectrum and frequent neurodevelopmental comorbidities. The aetiology of CP is poorly understood, despite recent reports of a genetic contribution in some cases. Here we demonstrate...
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