Article

Broadly effective ACE2 decoy proteins protect mice from lethal SARS-CoV-2 infection

2023-02-23

Abstract excerpt

As SARS-CoV-2 variants have been causing increasingly serious drug resistance problem, development of broadly effective and hard-to-escape anti-SARS-CoV-2 agents is in urgent need. Here we describe further development and characterization of two SARS-CoV-2 receptor decoy proteins, ACE2-Ig-95 and ACE2-Ig-105/106. We found that both proteins had potent and robust in vitro neutralization activities against diverse S...

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Literature Corpus work: da7017f2-17d1-5436-b4f9-f4d3e0d6bbc6
DOI: 10.1101/2023.02.22.529625

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