Article

Isolated prolapse of the posterior mitral valve leaflet: phenotypic refinement, heritability and genetic etiology

2024-10-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Isolated posterior leaflet mitral valve prolapse (PostMVP), a common form of MVP, often referred as fibroelastic deficiency, is considered a degenerative disease. PostMVP patients are usually asymptomatic and often undiagnosed until chordal rupture. The present study aims to characterize familial PostMVP phenotype and familial recurrence, its genetic background, and the pathop...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: da68e2e8-1c3a-5889-b7d6-522a64267ac0
DOI: 10.1101/2024.10.16.24315096

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Isolated prolapse of the posterior mitral valve leaflet: phenotypic refinement, heritability and genetic etiologyDOI 10.1101/2024.10.16.24315096Read

Genetics of syndromic and non-syndromic mitral valve prolapse.Semantic proximity Read

GWAS-driven Pathway Analyses and Functional Validation Suggest <i>GLIS1</i> as a Susceptibility Gene for Mitral Valve ProlapseSemantic proximity Read

Genetic Architecture and Myocardial Fibrotic Remodeling in Mitral Valve ProlapseSemantic proximity Read

Floppy mitral valve/mitral valve prolapse: A complex entity with multiple genotypes and phenotypes.Semantic proximity Read

Mild expression of mitral valve prolapse in the Framingham offspring: expanding the phenotypic spectrum.Semantic proximity Read

New insights into mitral valve dystrophy: a Filamin-A genotype-phenotype and outcome study.Semantic proximity Read

Genome-Wide Association Study–Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve ProlapseSemantic proximity Read

Characterization of LTBP2 mutation causing Mitral Valve ProlapseSemantic proximity Read

Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapseSemantic proximity Read

Genome-Wide Association Meta-Analysis Supports Genes Involved in Valve and Cardiac Development to Associate With Mitral Valve Prolapse.Semantic proximity Read

Characterization of LTBP2 mutation causing mitral valve prolapseSemantic proximity Read

Genome-wide association meta-analysis supports genes involved in valve and cardiac development to associate with mitral valve prolapseSemantic proximity Read