Article

7-Deshydroxypyrogallin-4-Carboxylic Acid Dietary Phytochemical as a Putative FTO Inhibitor in Breast Cancer: An Integrated Computational and Cytotoxicity Study

2026-05-28

Abstract excerpt

<title>Abstract</title> <p> Breast cancer is the most frequently diagnosed malignancy in women globally, representing a major global health burden, with a significant subset of cases exhibiting resistance to standard therapeutic regimens. Recently, m <sup>6</sup> A RNA demethylases such as FTO have been identified as important oncogenes in breast cancer, which modify the epitranscriptome of tumor cells to favo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: da3b7723-48ba-5cf5-8419-02f17bdc38f3
DOI: 10.21203/rs.3.rs-9715479/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

7-Deshydroxypyrogallin-4-Carboxylic Acid Dietary Phytochemical as a Putative FTO Inhibitor in Breast Cancer: An Integrated Computational and Cytotoxicity StudyDOI 10.21203/rs.3.rs-9715479/v1Read

Computational Identification of Druggable Bioactive Compounds from Catharanthus roseus and Avicennia marina against Colorectal Cancer by Targeting Thymidylate SynthaseSemantic proximity Read

Synthetic and Naturally Occurring Heterocyclic Anticancer Compounds with Multiple Biological TargetsSemantic proximity Read

Integrative study of phytochemicals for anti-fibroid agent: A perspective on protein networks, molecular docking, ADMET, simulation, DFT and bioactivitySemantic proximity Read

Integrative Transcriptomics and Phytochemical Screening Reveal Pratenol B, Eriodictyol, Losbanine, and Isookanin, as Potential EGFR and HRAS Inhibitors in Indian Oral Squamous Cell Carcinoma PatientsSemantic proximity Read

Computational evaluation of Fenugreek-derived compounds as FGFR2 inhibitors for cancer therapySemantic proximity Read

Mutant-Selective Binding of Phyllanthus niruri Phytochemicals to EGFR T790M: A Quantum-Classical Mechanistic Study.Semantic proximity Read

Identification of small molecular inhibitors of SIRT3 by computational and biochemical approaches a potential target of breast cancerSemantic proximity Read

Optimizing the resveratrol fragments for novel in silico hepatocellular carcinoma de novo drug designSemantic proximity Read

Exploring the Therapeutic Potential of Native Plant Compounds: Unveiling the Therapeutic Potential of Ferula gummosa in Colorectal Cancer through Bioinformatics and Experimental ValidationSemantic proximity Read

Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agentSemantic proximity Read

Next Generation Antineoplastic Agents: A Review on Structurally Modified Vinblastine (VBL) AnaloguesSemantic proximity Read

Control of Molecular Biochemistry and Cell Injury Responses through Highly Ordered Supramolecular Assembly of FlavonoidsSemantic proximity Read