Article
Integrative Transcriptomics and Phytochemical Screening Reveal Pratenol B, Eriodictyol, Losbanine, and Isookanin, as Potential EGFR and HRAS Inhibitors in Indian Oral Squamous Cell Carcinoma Patients
2025-12-02
Abstract excerpt
Oral squamous cell carcinoma (OSCC) is the most common head and neck cancer, with India contributing nearly one-third of the global cases. Management of OSCC remains difficult due to increasing risk factors, limited therapeutic options, severe side effects, and rising drug resistance. Therefore, novel and safer treatment strategies are urgently needed. This study explores the potential of phytochemicals as targete...
Topics
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- Berberine and alkaloids research
- Bioactive Compounds and Antitumor Agents
- Flavonoids in Medical Research
- Genomics, phytochemicals, and oxidative stress
- Natural product bioactivities and synthesis
- Phytochemicals and Antioxidant Activities
- PI3K/AKT/mTOR signaling in cancer
- Plant biochemistry and biosynthesis
Identifiers and source
- Literature Corpus work
- adedb146-1e6f-5395-b81d-9b0f025bae36
- DOI
- 10.64898/2025.11.28.691262
