Article

Circuitry dynamics of the cerebellum inform differential therapeutic responses and patient stratification in essential tremor

2026-02-05

Abstract excerpt

<title>Abstract</title> <p>Essential tremor (ET) is the most common movement disorder, yet fewer than 50% of patients respond to current pharmacological treatments. This study identifies spatiotemporal cerebellar neurodynamics as key determinants of differential therapeutic responses in two clinically linked ET mouse models: harmaline-induced (harmane toxicity) and Grid2dupE3 (climbing fiber overgrowth) mice. In...

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Literature Corpus work: da01b4bf-0b6c-52fa-bf0c-2ff1023d9ec0
DOI: 10.21203/rs.3.rs-8705665/v1

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