Article

Impact of a White Matter Reference Region on the Relationship between Florbetapir PET Measurements of Amyloid Plaque Deposition and Measurements of Cognitive Decline

2025-09-25

Abstract excerpt

The objective of this study was to systematically investigate both cross-sectional and longitudinal associations between amyloid PET tracer, Florbetapir (FBP), and cognition when different reference regions of interest – whole cerebellum versus white matter – are used for Standardized Uptake Value Ratio (SUVR) semi-quantification of amyloid beta deposition. Baseline and 2.2±0.4 year follow-up Florbetapir PET scans...

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Literature Corpus work: d9ce7c38-7284-53bf-8a3b-eb259a71c693
DOI: 10.1101/2025.09.19.25336123

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