Article
Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group.
PloS one - 1 Jan 2016
Su Yi, Blazey Tyler M, Owen Christopher J, Christensen Jon J, Friedrichsen Karl, Joseph-Mathurin Nelly, Wang Qing, Hornbeck Russ C, Ances Beau M, Snyder Abraham Z, Cash Lisa A, Koeppe Robert A, Klunk William E, Galasko Douglas, Brickman Adam M, McDade Eric, Ringman John M, Thompson Paul M, Saykin Andrew J, Ghetti Bernardino, Sperling Reisa A, Johnson Keith A, Salloway Stephen P, Schofield Peter R, Masters Colin L, Villemagne Victor L, Fox Nick C, Förster Stefan, Chen Kewei, Reiman Eric M, Xiong Chengjie, Marcus Daniel S, Weiner Michael W, Morris John C, Bateman Randall J, Benzinger Tammie L S
Abstract excerpt
Amyloid imaging plays an important role in the research and diagnosis of dementing disorders. Substantial variation in quantitative methods to measure brain amyloid burden exists in the field. The aim of this work is to investigate the impact of methodological variations to the quantification of amyloid burden using data from the Dominantly Inherited Alzheimer's Network (DIAN), an autosomal dominant Alzheimer's...
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