Article

Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis

2022-02-04

Abstract excerpt

Dialysis-related amyloidosis (DRA), a serious complication among long-term hemodialysis patients, is caused by amyloid fibrils of β 2 -microglobulin (β2m). Although high serum β2m levels and a long dialysis vintage are the primary and secondary risk factors for the onset of DRA, respectively, patients with these do not always develop DRA, indicating that there are additional risk factors. To clarify these unknown...

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Literature Corpus work: d9ca45d5-2afc-5bb9-b695-5e543bd16248
DOI: 10.1101/2022.02.01.478730

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