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Article

Systemic amyloidosis: lessons from β2-microglobulin.

The Journal of biological chemistry - 17 Apr 2015

Stoppini Monica, Bellotti Vittorio

Abstract excerpt

β2-Microglobulin is responsible for systemic amyloidosis affecting patients undergoing long-term hemodialysis. Its genetic variant D76N causes a very rare form of familial systemic amyloidosis. These two types of amyloidoses differ significantly in terms of the tissue localization of deposits and for major pathological features. Considering how the amyloidogenesis of the β2-microglobulin mechanism has been...

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Identifiers

PMID: 25750126
DOI: 10.1074/jbc.R115.639799
PMCID: PMC4400370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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