Article

Pharmaco-genetic screen to uncover actin regulators targeted by prostaglandins during <i>Drosophila</i> oogenesis

2019-08-01

Abstract excerpt

Prostaglandins (PGs) are lipid signaling molecules with numerous physiologic functions, including pain/inflammation, fertility, and cancer. PGs are produced downstream of cyclooxygenase (COX) enzymes, the targets of non-steroidal anti-inflammatory drugs (NSAIDs). In numerous systems, PGs regulate actin cytoskeletal remodeling, however, their mechanisms of action remain largely unknown. To address this deficiency,...

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Literature Corpus work: d951942b-7eef-51e7-90fb-07d9d4d1ff8a
DOI: 10.1101/722355

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