Article

Gut microbiota has a widespread and modifiable effect on host gene regulation

2017-10-27

Abstract excerpt

Variation in gut microbiome is associated with wellness and disease in humans, yet the molecular mechanisms by which this variation affects the host are not well understood. A likely mechanism is through changing gene regulation in interfacing host epithelial cells. Here, we treated colonic epithelial cells with live microbiota from five healthy individuals and quantified induced changes in transcriptional regulat...

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Identifiers and source

Literature Corpus work: d9436ca7-b992-55fa-94cc-544eccf1b2ff
DOI: 10.1101/210294

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