Article

Host transcriptional responses to gut microbiome variation arising from urbanism

2025-10-26

Abstract excerpt

<h4>ABSTRACT</h4> Gut microbiomes of urban communities are compositionally different from their rural counterparts, and are associated with immune dysregulation and gastrointestinal disease. However, it is unknown whether these compositional differences impact host physiology, and through what mechanisms. Here, we used human colonic epithelial cells to directly compare host transcriptional changes induced by gut...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 55f22b61-f7e4-57aa-9a9e-514cdf30d212
DOI: 10.1101/2025.10.26.683539

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Host transcriptional responses to gut microbiome variation arising from urbanismDOI 10.1101/2025.10.26.683539Read

Gut microbiome-mediated metabolism effects on immunity in rural and urban African populationsSemantic proximity Read

Impact of urbanization on gut microbiome mosaics across geographic and dietary contextsSemantic proximity Read

Gut Microbiome Changes with Acute Diarrheal Disease in Urban Versus Rural Settings in Northern EcuadorSemantic proximity Read

Urbanization associates with restricted gut microbiome diversity and delayed maturation in infantsSemantic proximity Read

Urbanisation and its associated factors affecting human gut microbiota: where are we heading to?Semantic proximity Read

Genetic and transcriptional analysis of human host response to healthy gut microbiomeSemantic proximity Read

Metagenomics Reveals Impact of Urbanisation in Central India on the Human Gut Microbiome and its Antimicrobial Resistance ProfilesSemantic proximity Read

Prevalence of Chronic Diseases and Alterations of Gut Microbiome in Ningxia China During Urbanization: An Epidemiological SurveySemantic proximity Read

Recent urbanization in China is correlated with a Westernized microbiome encoding increased virulence and antibiotic resistance genes.Semantic proximity Read

From sporulation to village differentiation: the shaping of the social microbiome over rural-to-urban lifestyle transition in IndonesiaSemantic proximity Read

Genetic and Transcriptional Analysis of Human Host Response to Healthy Gut MicrobiotaSemantic proximity Read

Distinct trajectories of urbanization shape the human gut microbiome across South AsiaSemantic proximity Read