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Article

Gut Microbiota Has a Widespread and Modifiable Effect on Host Gene Regulation

2 Sept 2019

Abstract excerpt

The composition of the gut microbiome has been associated with various aspects of human health, but the mechanism of this interaction is still unclear. We utilized a cellular system to characterize the effect of the microbiome on human gene expression. We showed that some of these changes in expression may be mediated by changes in chromatin accessibility. Furthermore, we validate the role of a specific microbe...

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PMID: 31481602
DOI: 10.1128/msystems.00323-18

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