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Article

Dectin-1 limits central nervous system autoimmunity through a non-canonical pathway

2020-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Pathologic roles for innate immunity in neurologic disorders are well-described, but protective aspects of the immune response are less understood. Dectin-1, a C-type lectin receptor (CLR), is largely known to induce inflammation. However, we found that Dectin-1 is protective in experimental autoimmune encephalomyelitis (EAE), while its canonical signaling mediator, Card9, promotes the disease....

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Literature Corpus work
d9398831-2db2-5c61-9fa4-343573b2f619
DOI
10.1101/2020.05.06.080481
Open publication

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Dectin-1 limits central nervous system autoimmunity through a non-canonical pathwayDOI 10.1101/2020.05.06.080481
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