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Article

Pattern recognition: recent insights from Dectin-1

1 Feb 2009

Abstract excerpt

The beta-glucan receptor Dectin-1 is an archetypical non-toll-like pattern recognition receptor expressed predominantly by myeloid cells, which can induce its own intracellular signalling and can mediate a variety of cellular responses, such as cytokine production. Recent identification of the components of these signalling pathways, such as Syk kinase, CARD9 and Raf-1, has provided novel insights into the...

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PMID: 19223162
DOI: 10.1016/j.coi.2009.01.003

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