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Article

Pattern Recognition Receptors in Multiple Sclerosis and Its Animal Models

12 Nov 2019

Abstract excerpt

Pattern recognition receptors (PRRs) coordinate the innate immune response and have a significant role in the development of multiple sclerosis (MS). Accumulating evidence has identified both pathogenic and protective functions of PRR signaling in MS and its animal model, experimental autoimmune encephalomyelitis (EAE). Additionally, evidence for PRR signaling in non-immune cells and PRR responses to host-derived...

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PMID: 31781124
DOI: 10.3389/fimmu.2019.02644

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