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Article

17 variants interaction of Wnt/β-catenin pathway associated with development of osteonecrosis of femoral head in Chinese Han population.

Scientific reports - 27 Mar 2024

Shi Chuankai, Li Xin, Sun Yu, Du Zhenwu, Zhang Guizhen, Che Zhenjia, Li Qingyu, Song Shiliang, Guo Jing, Sun Haoyan, Song Yang

Abstract excerpt

The genes of Wnt/β-catenin pathway may have potential roles in fat accumulation of Non-traumatic osteonecrosis of the femoral head (ONFH), but the effects of their variants in the pathway on ONFH development have been remained unclear. To explore the potential roles of the variants in the development of ONFH, we completed the investigation of the paired interactions as well as their related biological functions...

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Identifiers

PMID: 38538713
DOI: 10.1038/s41598-024-57929-8
PMCID: PMC10973331

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