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IPSILESIONAL HIPPOCAMPAL GABA IS ELEVATED AND CORRELATES WITH COGNITIVE IMPAIRMENT AND MALADAPTIVE NEUROGENESIS AFTER CORTICAL STROKE IN MICE

2022-11-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Cognitive dysfunction is a frequent stroke sequela but its pathogenesis and treatment remain unresolved. Involvement of aberrant hippocampal neurogenesis and maladaptive circuitry remodelling has been proposed but their mechanisms are unknown. Our aim was to evaluate potential underlying molecular/cellular events implicated. <h4>Methods</h4> Stroke was induced by permanent...

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Literature Corpus work: d9078ef9-90ad-500a-aae1-e945f47f3ebf
DOI: 10.1101/2022.11.02.514653

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