Article

Phytohemagglutinin-Activated CAR-T Cells: Prolonged Persistence and Enhanced Anti-Tumor Response in CD19-Specific Acute Lymphoblastic Leukemia

2023-07-15

Abstract excerpt

<h4>ABSTRACT</h4> In recent times, chimeric antigen receptor (CAR)-T cell therapy has shown rapid advancements and gained clinical approval for use in cancer immunotherapy. CAR, a synthetic receptor integrated into autologous T cells, has yielded highly successful results in patients with leukemia. The significant potential of CAR-T cells has been validated through clinical trials in adult and pediatric cancer tr...

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Literature Corpus work: d900cde0-ad17-5a9c-8bd4-507508166d35
DOI: 10.1101/2023.07.15.547808

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