Back to search

Article

Characterization of clinical significance of PD-1/PD-Ls expression and methylation in patients with low grade glioma

2020-03-20

Abstract excerpt

<h4>Background</h4> Immune checkpoints play crucial roles in immune escape of cancer cells. However, the exact prognostic values of expression and methylation of programmed death 1 (PD-1), programmed death-ligand 1 (PD-L1) and PD-L2 in low-grade glioma (LGG) have not been defined yet. <h4>Methods</h4> A total of 514 LGG samples from TCGA dataset containing both PD-1, PD-L1 and PD-L2 expression, DNA methylation,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d8f14cbb-4358-5353-b46e-ade9ff2b6359
DOI
10.1101/2020.03.20.999573
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Characterization of clinical significance of PD-1/PD-Ls expression and methylation in patients with low grade gliomaDOI 10.1101/2020.03.20.999573
Characterization of the Clinical Significance of PD-1/PD-Ls Expression and Methylation in Patients With Low-Grade Glioma.Semantic proximity
DSN1 may predict poor prognosis of lower-grade glioma patients and may be a potential target for immunotherapySemantic proximity
PODNL1 Methylation Serves as a Prognostic Biomarker and Associates with Immune Cell Infiltration and Immune Checkpoint Blockade Response in Lower-Grade Glioma.Semantic proximity
Molecular and clinical characterization of PD-L1 expression at transcriptional level via 976 samples of brain gliomaSemantic proximity
Mutational profiling of low-grade gliomas identifies prognosis and immunotherapy-related biomarkers and tumour immune microenvironment characteristics.Semantic proximity
PD-L1-related LncRNAs are Associated with Immune Microenvironment and Prognosis in GliomaSemantic proximity
Predictive Panel for Immunotherapy in Low-Grade Glioma.Semantic proximity
Profiles of PD-1, PD-L1, PD-L2 in Gastric Cancer and Their Relation with Mutation, Immune Infiltration, and Survival.Semantic proximity
Construction of an immune infiltration-associated ceRNA network and prognostic model for low-grade gliomasSemantic proximity
Enhanced B7-H4 expression in gliomas with low PD-L1 expression identifies super-cold tumorsSemantic proximity
A novel disulfidptosis-related lncRNA signature predicts prognosis and therapeutic response in low-grade gliomaSemantic proximity
DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in gliomaSemantic proximity
Select a neighboring publication to make it the new centre.