Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Profiles of PD-1, PD-L1, PD-L2 in Gastric Cancer and Their Relation with Mutation, Immune Infiltration, and Survival.

BioMed research international - 1 Jan 2020

Liu Jingwei, Li Hao, Sun Liping, Yuan Yuan, Xing Chengzhong

Abstract excerpt

BACKGROUND: Although multiple types of cancers demonstrated favorable outcome after immunotherapy of PD-1/PD-L1 blockade, the specific regulatory mechanism of PD genes in gastric cancer (GC) remains largely unknown. MATERIALS AND METHODS: Expression of RNA, copy number variants, and clinical parameters of GC individuals from TCGA were analyzed. Coexpressed genes for PD-1, PD-L1, and PD-L2 were selected by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B7-H1 Antigen
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphocyte Activation

Share to Programmed Cell Death 1 Receptor

Share to Protein Interaction Maps

Share to Stomach Neoplasms

Share to Transcriptome

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 32596285
DOI: 10.1155/2020/2496582
PMCID: PMC7298268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Profiles of PD-1, PD-L1, PD-L2 in Gastric Cancer and Their Relation with Mutation, Immune Infiltration, and Survival.PMID 32596285Read ↗

Comprehensive assessment of PD-L1 and PD-L2 dysregulation in gastrointestinal cancers.Semantic proximity Read ↗

Clinical Significance of Tumor and Immune Cell PD-L1 Expression in Gastric AdenocarcinomaSemantic proximity Read ↗

High PD-L1 expression in gastric cancer (GC) patients and correlation with molecular featuresSemantic proximity Read ↗

Polymorphism of the programmed death‐ligand 1 gene is associated with its protein expression and prognosis in gastric cancerSemantic proximity Read ↗

Pan-cancer analysis identifies PD-L2 as a tumor promotor in the tumor microenvironmentSemantic proximity Read ↗

Programmed death 1, ligand 1 and 2 correlated genes and their association with mutation, immune infiltration and clinical outcomes of hepatocellular carcinomaSemantic proximity Read ↗

M1-like TAMs are required for the efficacy of PD-L1/PD-1 blockades in gastric cancerSemantic proximity Read ↗

The genomic and immune landscapes of gastric cancer and their correlations with HER2 amplification and PD-L1 expression.Semantic proximity Read ↗

PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanismsSemantic proximity Read ↗

Identification and validation of a novel survival prediction model based on the T cell phenotype in tumor immune microenvironment and peripheral blood for the prognosis in gastric cancerSemantic proximity Read ↗

Elevated neutrophil-to-lymphocyte ratio induced by tumor and immune cells promotes gastric cancer progression during PD-1 antibody-based treatmentSemantic proximity Read ↗

Neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.