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Enhanced B7-H4 expression in gliomas with low PD-L1 expression identifies super-cold tumors

1 May 2020

Abstract excerpt

BACKGROUND: Characterizing expression profiles of different immune checkpoint molecules are promising for personalized checkpoint inhibitory immunotherapy. Gliomas have been shown as potential targets for immune checkpoint inhibitors recently. Our study was performed to determine coexpression levels of two major B7 immune regulatory molecules programmed death ligand 1 (PD-L1) and B7-H4, both of which have been...

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PMID: 32457124
DOI: 10.1136/jitc-2019-000154

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