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Article

Mutational profiling of low-grade gliomas identifies prognosis and immunotherapy-related biomarkers and tumour immune microenvironment characteristics.

Journal of cellular and molecular medicine - 1 Nov 2021

Lin Wen-Wen, Ou Guan-Yong, Zhao Wei-Jiang

Abstract excerpt

Low-grade glioma (LGG) is a heterogeneous tumour with the median survival rate less than 10 years. Therefore, it is urgent to develop efficient immunotherapy strategies of LGG. In this study, we analysed mutation profiles based on the data of 510 LGG patients from the Cancer Genome Atlas (TCGA) database and investigated the prognostic value of mutated genes and evaluate their immune infiltration. Tumor Immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34597473
DOI: 10.1111/jcmm.16947
PMCID: PMC8572778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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