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Article

Characterization of the Clinical Significance of PD-1/PD-Ls Expression and Methylation in Patients With Low-Grade Glioma.

Technology in cancer research & treatment - 1 Jan 2000

Mei Jie, Cai Yun, Xu Rui, Yang Xuejing, Zhou Weijian, Wang Huiyu, Liu Chaoying

Abstract excerpt

BACKGROUND: Immune checkpoints play crucial roles in the immune escape of cancer cells. However, the exact prognostic values of expression and methylation of programmed-death 1 (PD-1), programmed-death-ligand 1 (PD-L1) and PD-L2 in low-grade glioma (LGG) have not been well-defined yet. METHODS: A total 514 LGG samples from the Cancer Genome Atlas (TCGA) dataset containing gene expression, DNA methylation, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33955303
DOI: 10.1177/15330338211011970
PMCID: PMC8111557

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