Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carotid Plaque‐Derived Small Extracellular Vesicles Mediate Atherosclerosis and Correlate With Plaque Vulnerability

19 May 2025

Abstract excerpt

ABSTRACT Carotid plaque‐derived small extracellular vesicles (psEVs) offer insights into tissue‐ and disease‐specific pathobiology, but their roles in plaque vulnerability and their diagnostic potential remain unclear. Herein, we isolated psEVs from stable and vulnerable (intraplaque hemorrhage [IPH] or fibrous cap rupture [FCR]) plaques in patients with asymptomatic carotid artery stenosis (aCAS). Our findings...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis and Cardiovascular Diseases
Share to Cardiovascular Disease and Adiposity
Share to Extracellular vesicles in disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40391195
DOI: 10.1002/mco2.70220

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carotid Plaque‐Derived Small Extracellular Vesicles Mediate Atherosclerosis and Correlate With Plaque VulnerabilityPMID 40391195Read ↗

Multiomics unveils extracellular vesicle-driven mechanisms of endothelial communication in human carotid atherosclerosisSemantic proximity Read ↗

The Dual Role of Extracellular Vesicles in Atherosclerosis: From Pathogenic Mediators to Translational Tools in Diagnosis and Targeted TherapySemantic proximity Read ↗

Platelet-derived small extracellular vesicles (PDsEVs) sequencing unveils MEF2B as potential target in atherosclerosis-related diseasesSemantic proximity Read ↗

BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque.Semantic proximity Read ↗

High-Dimensional Single-Cell Multimodal Landscape of Human Carotid AtherosclerosisSemantic proximity Read ↗

Proteomics reveals spatial and molecular heterogeneities in advanced atherosclerotic carotid artery plaques.Semantic proximity Read ↗

Circulating Small Noncoding RNA Profiling as a Potential Biomarker of Atherosclerotic Plaque Composition in Type 1 DiabetesSemantic proximity Read ↗

Identification of FBLN5, mir128 and mir532-5p Related to Unstable Plaques in Carotid Atherosclerosis Patients by Single-Cell RNA SequencingSemantic proximity Read ↗

Proteomics and ex vivo plaque culture identify the insulin-like growth factor axis as a potential regulator of matrix remodelling in carotid plaques.Semantic proximity Read ↗

Single-nucleus RNA sequencing reveals that macrophages and smooth muscle cells promote carotid atherosclerosis progression through mitochondrial autophagySemantic proximity Read ↗

Proteomics of plaques and novel sources of potential biomarkers for atherosclerosisSemantic proximity Read ↗

Autophagic Marker MAP1LC3B Expression Levels Are Associated with Carotid Atherosclerosis SymptomatologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.