Article

Freeze-thaw decellularization of the trabecular meshwork in an <i>ex vivo</i> eye perfusion model

2017-02-05

Abstract excerpt

<h4>Objective: </h4> Trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might represent a novel therapeutic breakthrough. Various decellularized TM scaffolds were developed by ablating existing cells with suicide gene therapy or saponin, but always with incomplete cell removal or dissolve the extracellular matrix. W...

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Literature Corpus work: d8e1dc10-4abb-5571-a06e-2e569e13c5fe
DOI: 10.7287/peerj.preprints.2736v3

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