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Transplantation of iPSC-TM stimulates division of trabecular meshwork cells in human eyes

19 Feb 2020

Abstract excerpt

The trabecular meshwork's (TM) physiological role is to maintain normal intraocular pressure by regulating aqueous humor outflow. With age, and particularly in eyes with primary open angle glaucoma, the number of cells residing within the TM is markedly decreased and the function of the tissue is compromised. Here we evaluate if transplantation of induced pluripotent stem cell derived TM like cells (iPSC-TM)...

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PMID: 32076077
DOI: 10.1038/s41598-020-59941-0

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