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Article

Simultaneously induced mutations in eIF4E genes by CRISPR/Cas9 enhance PVY resistance in tobacco.

Scientific reports - 26 Aug 2022

Le Ngoc Thu, Tran Huyen Thi, Bui Thao Phuong, Nguyen Giang Thu, Van Nguyen Doai, Ta Dong Thi, Trinh Duy Dinh, Molnar Attila, Pham Ngoc Bich, Chu Ha Hoang, Do Phat Tien

Abstract excerpt

Tobacco is an important commercial crop and a rich source of alkaloids for pharmaceutical and agricultural applications. However, its yield can be reduced by up to 70% due to virus infections, especially by a potyvirus Potato virus Y (PVY). The replication of PVY relies on host factors, and eukaryotic translation initiation factor 4Es (eIF4Es) have already been identified as recessive resistance genes against...

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Identifiers

PMID: 36028578
DOI: 10.1038/s41598-022-18923-0
PMCID: PMC9418239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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