Article

Induction of apoptosis and change of bcl—2 expression in macrophage Ana—1 cells by all—trans retinoic acid

1996-01-01

Abstract excerpt

Macrophage cells play an important role in the initiation and regulation of the immune response.All-trans retinoic acid (ATRA) and its natural and synthetic analogs (retinoids)affect a large number of biological processes.Recently,retinoids have been shown promise in the therapy and prevention of various cancers.However,many interesting questions related to the activities of retinoids remain to be answered:(I) Mol...

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Literature Corpus work: d8bd7510-f601-57e8-b1f2-8359c1ba48d3
DOI: 10.1038/cr.1996.15

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