Article

Rapid residual bead quantification for cell therapy manufacturing using Raman spectroscopy

2026-03-04

Abstract excerpt

Adoptive cell therapies are transforming the treatment of cancer and autoimmunity by enhancing patients’ own immune cells to fight disease. In cell therapy manufacturing, immunomagnetic beads are used to isolate and activate target cells for gene transfer but must be removed downstream to ≤10 beads per 300,000 cells. Current quantification requires time-intensive and error-prone manual counting using brightfield m...

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Literature Corpus work: d8a5111f-8201-5ceb-8292-a055567d0d73
DOI: 10.64898/2026.03.02.709071

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