Article

Cognitive and inflammatory heterogeneity in severe mental illness: Translating findings from blood to brain

2023-11-03

Abstract excerpt

Recent findings link cognitive impairment and inflammatory-immune dysregulation in schizophrenia (SZ) and bipolar (BD) spectrum disorders. However, heterogeneity and translation between the periphery and central (blood-to-brain) mechanisms remains a challenge. Starting with a large SZ, BD and healthy control cohort ( n =1235), we aimed to i) identify candidate peripheral markers ( n =25) associated with cognitive...

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Literature Corpus work: d8918bac-9d08-512d-a9de-754df32f3636
DOI: 10.1101/2023.11.02.23297924

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