Article
Evidence that a working memory cognitive phenotype within schizophrenia has a unique underlying biology.
Psychiatry research - 1 Nov 2022
Dean Brian, Thomas Elizabeth H X, Bozaoglu Kiymet, Tan Eric J, Van Rheenen Tamsyn E, Neill Erica, Sumner Philip J, Carruthers Sean P, Scarr Elizabeth, Rossell Susan L, Gurvich Caroline
Abstract excerpt
It is suggested studying phenotypes within the syndrome of schizophrenia will accelerate understanding the complex molecular pathology of the disorder. Supporting this hypothesis, we have identified a sub-group within schizophrenia with impaired working memory (WM) and have used Affymetrix™ Human Exon 1.0 ST Arrays to compare their blood RNA levels (n=16) to a group of with intact WM (n=18). Levels of 72 RNAs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.